CCO Infectious Disease Podcast

Long-Acting PrEP: Strategies to Support PrEP Persistence and Reengagement

Episode Summary

Hear from Sarah M. Wood, MD, MS, in this case-based discussion of the data and recommendations for initiating long-acting PrEP for a transgender adolescent patient as a strategy to support PrEP persistence and engagement.

Episode Notes

In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including: 

• The PrEP care continuum for adolescents
• System barriers to PrEP coverage and privacy concerns for adolescents
• The benefits and challenges of same-day PrEP initiation and real-world data to support it
• Interventions to support PrEP persistence
• PrEP options for different populations and the data to support the efficacy of long-acting cabotegravir (CAB) PrEP from HPTN 083 and HPTN 084
• Data and recommendations for a CAB PrEP oral lead-in
• Data from HPTN 083 showing no interaction between feminizing hormone therapy and long-acting CAB PrEP
• Project LifeSkills: a culturally specific, empowerment-based, group-delivered behavioral HIV prevention intervention for young transgender women

Faculty

Sarah M. Wood, MD, MS
Assistant Professor of Pediatrics 
Division of Adolescent Medicine
Perelman School of Medicine
University of Pennsylvania 
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Follow along with the slides: 
https://bit.ly/3Ha9Kmt

Link to full program: 
https://bit.ly/3ZlICsL

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