CCO Infectious Disease Podcast

All Eyes on ExPEC: A Major Driver of Invasive Disease and Antimicrobial Resistance

Episode Summary

Listen to expert insights on key concepts of ExPEC, including virulence factors associated with invasive disease, antimicrobial resistance profiles observed in clinical practice, populations at risk for invasive disease, and the current landscape of vaccine development.

Episode Notes

In this episode, Lilian Abbo, MD, FIDSA; Julie Ann Justo, PharmD, MS; and David van Duin, MD, PhD, FIDSA, FAST, discuss key concepts about extraintestinal pathogenic Escherichia coli, including:

• Diverse strains and virulence factors associated with invasive disease
• Antimicrobial resistance profiles seen in clinical practice
• Various disease manifestations
• Prevalence and burden of invasive infections
• Populations at risk
• Risk factors for multidrug-resistant strains
• Emerging vaccine technologies
• Active clinical trials 
• Benefits of vaccines and the challenges associated with development
• Importance of antimicrobial stewardship and potential role of vaccines to reduce antimicrobial resistance

Program Director: 
Lilian Abbo, MD, FIDSA
Associate Chief Medical Officer in Infectious Diseases
Jackson Health System
Professor of Infectious Diseases
Department of Medicine & Miami Transplant Institute
University of Miami Miller School of Medicine
Miami, Florida

Faculty:
Julie Ann Justo, PharmD, MS
Clinical Associate Professor
Department of Clinical Pharmacy and Outcomes Sciences
University of South Carolina College of Pharmacy
Infectious Diseases Clinical Pharmacy Specialist
Department of Pharmacy
Prisma Health Richland Hospital
Columbia, South Carolina

David Van Duin, MD, PhD, FIDSA, FAST
Professor of Medicine 
Director, Immunocompromised Host Infectious Diseases Program
Division of Infectious Diseases
University of North Carolina
Chapel Hill, North Carolina

Content based on a CME program supported by an educational grant from Janssen Therapeutics.

Follow along with a downloadable slideset at:
https://bit.ly/3eG29Bn

Link to full program:
https://bit.ly/3eFHfCl