CCO Infectious Disease Podcast

Integration of Genotypic RDT With Rapid Phenotypic AST for Bloodstream Infections

Episode Summary

Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs.

Episode Notes

Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs. Topics covered include:

• Typical patterns of intrinsic antibiotic susceptibility and resistance in Enterobacterales
• Mechanisms of resistance in gram-negative bacteria
• Genotypic rapid diagnostic tests for BSIs
• Resistance markers for earlier targeted therapy
• Rapid phenotypic antimicrobial susceptibility test platforms for blood cultures

Presenter:

Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP)
Medical and Public Health Microbiologist
Medical and Technical Director of Microbiology
AdventHealth
Orlando, Florida

Link to full program and downloadable slides:
https://bit.ly/4inoXCx

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